Area of Research:

Our research is involved in exploring and understanding biological systems at the molecular level with a tool set offered by modern chemistry. We work in the interface of organic chemistry and cell biology and manipulation of cellular activity with bio-active molecules.

We believe that not only discovery of right bioactive molecules but also delivery of the molecules to the particular site of action is equally challenging.

Our major focus includes:

Ø  Development of subtype specific histone deacetylase (HDAC) inhibitors/activators as epigenetic modulators mainly potent and isoform selective HDAC inhibitors with fairly acceptable blood brain barrier permeability to understand the individual isoform of HDAC responsible to turn on or turn off the transcription machineries involved with the genes responsible for the improvement of cognition, memory and mood stabilization of patients suffering from depression and dementia.

Ø  Exploration of epigenetic modulators as the emerging treatment strategy to combat different forms of cancer

Ø  Discovery of promising drug candidates for the treatment of cancer in collaboration with different drug discovery researchers.

Ø  Development of biocompatible polymeric drug delivery cargo with the help of polymer chemistry to bring the drugs at the site of action with less off target effects in collaboration with different drug delivery experts.