Publications

Papers in National/ International Journals

75. Yogesh Mahadu Khetmalis, Guruvelli Padma Vijaya Sangeetha,Ala Chandu,Swati,Sankaranarayanan Murugesan,Vivek Sharma,Muthyala Murali Krishna Kumar, Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis, and Biological Evaluation of Novel Oxindole Analogs as Anti-Tubercular Agents. Future Medicinal Chemistry 2023 (accepted).

74. Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Boddupalli Venkata Siva kumar, Ala Chandu, Banoth Karan Kumar, Gauri Shetye, Rui Ma, Sankaranarayanan Murugesan, Scott G. Franzblau, Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis and Biological Evaluation of Phenanthridine Amide and 1,2,3-Triazole Analogues against Mycobacterium tuberculosis. RSC Medicinal Chemistry, 2023 (accepted manuscript: DOI: 10.1039/D3MD00115F).

73. Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Guruvelli Padma Vijaya Sangeetha, Ala Chandu, Swati, Muthyala Murali Krishna Kumar, Vivek Sharma, Sankaranarayanan Murugesan, and Kondapalli Venkata Gowri Chandra Sekhar*, Tetrahydroisoquinoline based 5-Nitro-2-furoic acid Derivatives: A Promising New Approach for Anti-Tubercular Agents, New Journal of Chemistry, 2023 (in press).

72. Yogesh Mahadu Khetmalis, Ashna Fathima, Markus Schweipert, Cécile Debarnot, Naga Venkata Madhusudhan Rao Bandaru, Sankaranarayanan Murugesan, Trinath Jamma, Franz-Josef Meyer-Almes and Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity, International Journal of Molecular Sciences 2023, 24 (13), 11044.

71. M. Abirami, Banoth Karan Kumar, Faheem, Sanchita Dey, Samridhi Johri, Rosa M. Reguera, Rafael Bala˜na-Fouce, Kondapalli Venkata Gowri Chandra Sekhar, Murugesan Sankaranarayanan, Molecular-level strategic goals and repressors in Leishmaniasis – Integrated data to accelerate target-based heterocyclic scaffolds, European Journal of Medicinal Chemistry, 2023, 257, 115471.

70. Savita, Adinarayana Nandikolla, Adarash Kumar Shukla, Kondapalli Venkata Gowri Chandra Sekhar and Anupam Bhattacharya, Visible light sensing of ions by a cynoquinoxaline 1,4-dioxide-based probe and its applications. Dalton Transactions, 2023, 52, 4103.

69. Yogesh Mahadu Khetmalis, Bakhya Shree, Boddupalli Venkata Siva Kumar, Markus Schweipert, Cécile Debarnot, Fathima Ashna, Murugesan Sankaranarayanan, Jamma Trinath, Vivek Sharma, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar*, Design, synthesis, and biological evaluation of tetrahydroisoquinoline based hydroxamate derivatives as HDAC 6 inhibitors for cancer therapy. Journal of Molecular Structure, 2023, 1278, 134952.

68. Bodupalli Venkata Siva Kumar, Yogesh Mahadu Khetmalis, Adinarayana Nandikolla, Banoth Karan Kumar, Kevin Van Calster, Sankaranarayanan Murugesan, Davie Cappoen, and Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis, and Antimycobacterial Evaluation of Novel Tetrahydroisoquinoline Hydrazide Analogs, Chemistry & Biodiversity 2023, 20, e202200939.

67. Samridhi Johri, Banoth Karan Kumar, Sanchita Dey, Faheem, Rafael Balana-Fouce, Kondapalli Venkata Gowri Chandra Sekhar*, Selvaraj Kunjiappan, Sankaranarayanan Murugesan, Inspection of in-house designed novel thiochromone amino-acid conjugate derivatives as Lm-NMT inhibitor – An in-silico analysis. Journal of Molecular Graphics and Modelling 2023, 119, 108397.

66. Snehal Rajkumar Jadhav, Banoth Karan Kumar, Renuka Parshuram Joshi, Chougule Kishor Suryakant, Ala Chandu, Mohammed Muzaffar-Ur-Rehman, Yogesh Mahadu Khetmalis, Adinarayana Nandikolla, Sankaranarayan Murugesan and Kondapalli Venkata Gowri Chandra Sekhar*, Retrospective Review of Chromane Analogues as Anti-Protozoal Leads: A Decade's Worth of Evolution. Current Topics in Medicinal Chemistry, 2023, 23 (9), 713-735.

65. Ravi Kiran Panchakarla, Punna Rao Ravi, Manidhar Syam Kumar Buddha, Sumanth Mullangi, and Kondapalli Venkata Gowri Chandra Sekhar*, In silico toxicity assessment and trace level quantification of two genotoxic impurities in silodosin using capillary gas chromatography, Journal of Analytical Science and Technology, 2023 (https://doi.org/10.1186/s40543-023-00378-1).

64. Surendar Chitti, Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Kevin Van Calster, Boddupalli Venkata Siva Kumar, Banoth Karan Kumar, Sankaranarayanan Murugesan, Davie Cappoen, and Kondapalli Venkata Gowri Chandra Sekhar *, Design, Synthesis and Biological Evaluation of Novel Spiro-[chroman-2,4'-piperidin]-4-one Analogues as Anti-Tubercular Agents. Chemistry & Biodiversity 2022, e202200304.

63. Surendar Chitti, Kevin Van Calster, Davie Cappoen, Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Paul Cos, Banoth Karan Kumar, Sankaranarayanan Murugesan and Kondapalli Venkata Gowri Chandra Sekhar* Design, synthesis and biological evaluation of benzo-[d]-imidazo-[2,1-b]-thiazole and imidazo-[2,1-b]-thiazole carboxamide triazole derivatives as antimycobacterial agents. RSC Advances 2022, 12, 22385–22401.

62. Adinarayana, N., Yogesh, M. K., Mahalakshmi Naidu, K., Karan Kumar, B., Murugesan, S.,Chandra Sekhar, K.V.G.* Discovery of potent antitubercular agents: Design, synthesis and biological evaluation of 4-(3-(4-substitute dpiperazin-1-yl)-quinoxalin-2-yl)-naphthalen-1-ol analogues. Toxicol. in Vitro 82 (2022) 105370.

61. Adinarayana, N., Srinivasarao, S., Karan Kumar, B., Murugesan, S., Aggarwal, H., Balaña-Fouce, R., Melcón-Fernandez., Chandra Sekhar, K.V.G*. Design, synthesis and evaluation of novel phenanthridine triazole analogs as potential antileishmanial agents. Future Med. Chem. 2022, 14 (12), 867-880.

60.Faheem, Sanchita, D., Samridhi, J., M. Abirami, Karan Kumar, B., Donatella, T., Nicoletta, B., Rafael B. F., Murugesan, S., Chandra Sekhar, K.V.G., Search for structurally diverse heterocyclic analogs as dual-acting antimalarial and antileishmanial agents: An overview. Eur. J. Med. Chem. Reports. 2022, 4, 100031.

59. Yogesh, M, K., Surendar, C., Anjani, U. W., Karan Kumar, B., Murali Krishna Kumar M., Murugesan, S., Chandra Sekhar, K.V.G*. Design, Synthesis and Anti-mycobacterial Evaluation of Imidazo-[1,2-a]-pyridine Analogues. RSC Med. Chem. 2022, 13, 327-342.

58. Archana, B., N.V.M. Rao, B., Raghurami Reddy, B., Suraj, T.G., Subhendu, M., Wesley Roy, B., Sumanth Kumar V., Krishna Satya Alapati, Chandra Sekhar, K.V.G., Kavitha, N., Chandrasekhar, A., Susanta, Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders. Bioorg. Med. Chem. Lett. 2022, 55, 128448.

57. Surendar, C., Sravani, P., Adinarayana, N., Tarun Kumar, P., Karan Kumar, B., Murugesan, S., Balaram, G., Chandra Sekhar, K.V.G*. Design, Synthesis and SAR Studies of Novel Spirochromanone hydrochloride Analogues as Anticancer Agents. Future Med. Chem. 2022, 22 (5), 325-342.

56. Karan Kumar, B., Faheem., Rafael B. F., Estela M. F., Yolanda, Rosa M. R., Adinarayana, N., Chandra Sekhar, K.V.G., Murugesan, S. Design, synthesis and evaluation of novel β-carboline ester analogues as potential anti-leishmanial agents. J. Biomol. Struct. Dyn. 2021, DOI: 10.1080/07391102.2021.1973564.

55. Nandikolla, A., Srinivasarao, S., Kumar, B.K., Murugesan, S., Aggarwal, H., Balaña-Fouce, R., Melcón-Fernandez, E., Pérez-Pertejo, Y., Chandra Sekhar, K.V.G*. Novel phenanthridine amide analogs as potential anti-leishmanial agents: In vitro and in silico insights. Bioorg. Chem., 2021, 117, 105414.

54. Faheem., Karan Kumar, B., Chandra Sekhar, K.V.G., Subhash Chander, Selvaraj, K., Murugesan, S. 1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design. Expert Opin. Drug Discov., 2021, 16(10), 1119-114.

53. Ravi Kiran P., Punna Rao, R., Chandra Sekhar, K.V.G*. Liquid chromatography‑tandem mass spectrometric method for trace quantification of ethyl methanesulfonate: a genotoxic impurity in dapoxetine hydrochloride. Future J. Pharm. Sci. 2021, 7, 191.

52. Shivani, M., Adinarayana, N., Murugesan, S., Chandra Sekhar, K.V.G*. 1,8-Naphthyridine derivatives: an updated review on recent advancements of their myriad biological activities. Future Med. Chem., 2021, 13(18), 1591-1618.

51. Yogesh, M, K., Shivani, M., Murugesan, S., Chandra Sekhar, K.V.G*. Oxindole and its derivatives: A review on recent progress in biological activities. Biomed. Pharmacother. 2021, 141, 111842.

50. Surendar, C., Sravani, P., Adinarayana, N., Tarun Kumar, P., Karan Kumar, B., Murugesan, S., Balaram, G., Chandra Sekhar, K.V.G*. Design, synthesis and biological evaluation of 7–(5–((substituted – amino)-methyl)-thiophen–2–yl)-spiro-[chroman–2,4′–piperidin]–4–one hydrochloride analogues as anticancer agents. Bioorg. Chem., 2021, 112, 104865.

49. Adinarayana, N., Srinivasarao, S., Yogesh, M.K., Karan Kumar, B., Murugesan, S., Gauri, S., Rui M., Scott, G. F., Chandra Sekhar, K.V.G*. Design, synthesis and biological evaluation of novel 1,2,3-triazole analogues of Imidazo-[1,2-a]-pyridine-3-carboxamide against Mycobacterium tuberculosis. Toxicol. In Vitro, 2021, 74, 105137.

48. Faheem, Karan Kumar, B., Chandra Sekhar, K.V.G, Subhash, C., Selvaraj K, Murugesan, S.Medicinal chemistry perspectives of 1,2,3,4-tetrahydroisoquinoline analogs – biological activities and SAR studies. RSC Adv., 2021, 11, 12254–12287.

47. Karan Kumar, B., Faheem, Chandra Sekhar, K.V.G., Rupal O., Vijay Kumar P., Aravinda Pai, Murugesan, S., Pharmacophore based virtual screening, molecular docking, molecular dynamics and MMGBSA approach for identification of prospective SARS-CoV-2 inhibitor from natural product databases. J. Biomol. Struct. Dyn. 2021, (in press – DOI: 0.1080/07391102.2020.1824814).

46. Ravi Kiran P, Punna Rao R, Chandra Sekhar, K.V.G*. Selective and Sensitive UHPLC Method for the Trace Analysis of Formaldehyde in Drug Substance Using Fused-core Column Technology and Detailed Pre-column Derivatization study. Curr. Pharm. Anal., 2021, 17, 201-209.

45. Faheem, Karan Kumar, B., Chandra Sekhar, K.V.G, Selvaraj K, Joazaizulfazli J, Rafael B, Murugesan, S. Recent update on the anti-infective potential of β-carboline analogs. Mini-Rev. Med. Chem. 2021, 21, 398 – 425.

44. Adinarayana, N., Srinivasarao, S., Karan Kumar, B., Murugesan, S., Himanshu A., Louise, L.M., Terry, K.S., Chandra Sekhar, K.V.G*. Synthesis, study of antileishmanial and antitrypanosomal activity of imidazo pyridine fused triazole analogues. RSC Adv., 2020, 10, 38328-38343.

43. Suresh, A., Srinivasarao, S., Yogesh, M. K., Shashidhar, N., Murugesan, S., Chandra Sekhar, K.V.G*. Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis – a medicinal chemist perspective. RSC Adv., 2020, 10, 37098-37115.

42. Faheem, Karan Kumar, B., Chandra Sekhar, K.V.G., Selvaraj, K., Joazaizulfazli, J., Rafael, B. F., Babu, L.T., Murugesan, S. Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19. Bioorg. Chem., 2020, 104, 104269.

41. Karan Kumar, B., Faheem, Chandra Sekhar, K.V.G, Adinarayana, N., Murugesan, S. Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives – An update. Heliyon, 2020, 6, e04916.

40. Srinivasarao, S., Adinarayana, N., Suresh, A., Agnieszka, E., Agnieszka, G., Balaram, G., Karankumar, B., Murugesan, S., Sravani, P., Himanshu A., Chandra Sekhar, K.V.G*. Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agents. Bioorg. Chem., 2020, 100, 103955.

39. Srinivasarao, S., Adinarayana, N., Suresh, A., Kevin Van C, Linda De V, Davie C., Balaram, G., Himanshu A., Murugesan, S., Chandra Sekhar, K.V.G*. Seeking potent anti-tubercular agents: design and synthesis of substituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agents. RSC Adv., 2020, 10, 12272-12288.

38. Srinivasarao, S., Adinarayana, N., Shashidhar, N., Tsz, T.Y., Sravani, P., Balaram, G., Murugesan, S., Naresh, K., Chandra Sekhar, K.V.G*. Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimidazoles as novel inhibitors of LasR dependent Quorum Sensing in Pseudomonas aeruginosa. RSC Adv., 2019, 9, 29273-29292.

37. Surendar, C., Srinivasarao, S., Santosh, P.K.R., Prakruti, T., Yamini, B., Chandan, K., Krishnan, R., Balaram, G., Chandra Sekhar, K.V.G*. Design, synthesis and biological evaluation of 2-(3,4-dimethoxyphenyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridine analogues as antiproliferative agents. Bioorg. Med. Chem. Lett., 2019, 29, 2551-2558.

36. Suresh, N., Surendar, C., Suresh, A., Sridhar, G., Mallika, A., Debanjan, B., Nishant, J., Chandra Sekhar, K.V.G*. Design, Synthesis, and Biological Evaluation of 2-(4-Aminophenyl) benzothiazole Analogues as Antiproliferative Agents, J. Het. Chem, 2019, 56, 520-532.

35. Arun kumar, T., Ratnakaram V. N., Srinivasu, N., Yamini, B., Balaram, G., Chandra Sekhar, K.V.G*., Design, synthesis and anti-tumour activity of new pyrimidine-pyrrole appended triazoles. Toxicol. In Vitro, 2019, 60, 87–96.

34. Mahalakshmi Naidu, K., Rudresh Naik, G., Chandra Sekhar, K.V.G.* Design, synthesis and biological evaluation of 5-(2-(4-(substitutedbenzo[d]isoxazol-3-yl)piperazin-1-yl)acetyl)indolin-2-one and 5-(2-(4-substituted piperazin-1-yl)acetyl)indolin-2-one analogues as novel anti-tubercular agents. Arab. J. Chem. 2019, 12, 2418-2429.

33. Nagesh, H.N., Srinivasarao, S., Suresh, A., Nizalapur, S., Murugesan, S., Kanneboina, K., Kumar, N., Chandra Sekhar, K.V.G*. Sulfur-Assisted Deprotection of Methylene Nitrile Group: One-Pot Synthesis of 4-Substituted-2H-1,2,3-triazoles. Chemistry Select, 2018, 3, 7565-7571.

32. Chander, S., Ashok, P., Reguera, R., Perez, M., Andres, R., Rafael, B., Chandra Sekhar, K.V.G., Murugesan, S. Synthesis and activity of benzopiperidine, benzopyridine and phenyl piperazine based compounds against Leishmania infantum. Exp. Parasitol., 2018, 189, 49-60.

31. Srinivasarao, S., Nizalapur, S., Yu T T., Wenholz, D.S., Trivedi, P., Ghosh, B., Rangan, K., Kumar, N., Chandra Sekhar, K.V.G*. Design, Synthesis and Biological Evaluation of Triazole-Containing 2-Phenylindole and Salicylic Acid as Quorum Sensing Inhibitors against Pseudomonas aeruginosa, Chemistry Select, 2018, 3, 9170-9180.

30. Suresh N., Suresh A., Suresh Y., Manikapal, B., Mallika, A., Chandra Sekhar, K.V.G*. Anti-proliferative activity, molecular modeling studies and interaction with calf thymus DNA of novel ciprofloxacin analogues. J Chem. Sci., 2018, 130, 121.

29. Suresh, A., Srinivasarao, S., Agnieszka, Ewa, Mallika, A., Lherbet, C, Chandra Sekhar, K.V.G*. Design, synthesis of 9H-fluorenone based 1,2,3-triazole analogues as Mycobacterium tuberculosis InhA inhibitors. Chem. Biol. Drug Des. 2017, 91, 1078-1086.

28. Suresh, N, Chitti S, Suresh, A, Bhattacharjee D, Rao BB, Jain N, Alvala M, Chandra Sekhar, K.V.G*. Design and synthesis of 4-morpholino-6-(1,2,3,6-tetrahydropyridin-4-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine analogues as tubulin polymerization inhibitors. Bioorg. Med. Chem. Lett., 2017, 27, 3794-3801.

27. Lindemann, M., Deuther-Conrad, W., Moldovan, R., Brust, P., Wenzel, B., Chandra Sekhar, K.V.G., Do spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter? Bioorg. Med. Chem. 2017, 25, 5107-5113.

26. Suresh, A., Mahalakshmi Naidu K., Srinivasarao, S., Agnieszka,N., Ewa, AK., Misra, S., Murugesan, S., Chander, S., Krishnan, R., Chandra Sekhar, K.V.G*. Identification and development of pyrazolo[4,3-c]-pyridine carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors. New J. Chem., 2017, 41, 347-357.

25. Mahalakshmi Naidu K., Srinivasarao, S., Agnieszka,N., Ewa, A-K., Chandra Sekhar, K.V.G*., Seeking potent anti-tubercular agents: Design, synthesis, anti-tubercular activity and docking study of various ((triazoles/indole)-piperazin-1-yl/1,4-diazepan-1-yl)benzo[d]isoxazole derivatives. Bioorg. Med. Chem. Lett. 2016, 26, 2245-2250.

24. Suresh, N., Surendar, C., Bhaskara Rao, B., Mallika, A., Nishant J., Chandra Sekhar, K. V. G*., Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA. Eur. J. Med. Chem. 2016, 114, 220-231.

23. Suresh, A., Suresh, N., Misra, S., Krishna Kumar, M.M., Chandra Sekhar, K.V.G*., Design, Synthesis and Biological Evaluation of New Substituted Sulfonamide Tetrazole Derivatives as Antitubercular Agents. Chemistry Select, 2016, 1, 1705-1710.

22. Nagesh, H.N., Suresh, A., Reddy, M.N., Suresh, N., Subbalakshmi, J., Chandra Sekhar, K.V.G*., Multicomponent cascade reaction: dual role of copper in the synthesis of 1,2,3-triazole tethered benzimidazo[1,2-a]quinoline and their photophysical studies. RSC Adv., 2016, 6, 15884-15894.

21. Goh, W., Gardner, C. R., Chandra Sekhar, K.V.G., Biswas, N. N., Shashidhar, N., Rice, S.C., Willcox, M., Black, D. S., Kumar, N., Synthesis, quorum sensing inhibition and docking studies of 1,5-dihydropyrrol-2-ones. Bioorg. Med. Chem., 23, 7366-7377, 2015.

20. Mahalakshmi Naidu, K., Nagesh, H.N., Singh, M., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G*., Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors. Eur. J. Med. Chem. 2015, 92, 415-426.

19. Nagesh, H.N., Suresh, N., Bhanu Prakash, G.V.S., Gupta, S., Rao, J.V., Chandra Sekhar, K.V.G* Design, synthesis and biological evaluation of novel phenanthridinyl piperazine triazoles via click chemistry as anticancer agents. Med. Chem. Res. 2015, 24, 523-532.

18. Mahalakshmi Naidu, K., Suresh, A., Subbalakshmi, J., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G*

Raghavaiah, P. Design, synthesis and antimycobacterial activity of various 3-(4-substituted sulfonylpiperazin-1-yl)benzo[d]isoxazole derivatives. Eur. J. Med. Chem. 2014, 87, 71-78.

17. Nagesh, H.N., Suresh, A., Sairam, S.D.S.S., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G.* Design, synthesis and antimycobacterial evaluation of 1-(4-(2-substitutedthiazol-4-yl)phenethyl)-4-(3-(4-substitutedpiperazin-1-yl)alkyl)piperazine hybrid analogues. Eur. J. Med. Chem. 2014, 84, 605-613.

16. Nagesh, H.N., Suresh, N., Mahalakshmi Naidu, K., Arun, B., Sridevi, J.P., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G*. Synthesis and evaluation of anti-tubercular activity of 6-(4-substitutedpiperazin-1-yl) phenanthridine analogues. Eur. J. Med. Chem. 2014, 74, 333-339.

15. Suresh, N., Nagesh, H.N., Renuka, J., Rajput, V., Sharma, R., Khan, I.A., Chandra Sekhar, K.V.G*. Synthesis and evaluation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2-(4-substitutedpiperazin-1-yl)acetyl) piperazin-1-yl)quinoline-3-carboxylic acid derivatives as anti-tubercular and antibacterial agents. Eur. J. Med. Chem. 2014, 71, 324-332.

14. Suresh, N., Nagesh, H.N., Anil Kumar, Shirazi, A.N., Parang, K., Chandra Sekhar, K.V.G*. Synthesis of novel ciprofloxacin analogues and evaluation of their anti-proliferative effect on human cancer cell lines. Bioorg. Med. Chem. Lett. 2013, 23 (23), 6292-6295.

13. Nagesh, H.N., Mahalakshmi Naidu, K., Harika Rao, D., Sridevi, J.P., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G*. Design, synthesis and evaluation of 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1yl) phenanthridine analogues as antimycobacterial agents. Bioorg. Med. Chem. Lett. 2013, 23 (24), 6805-6810.

12. Chandra Sekhar, K.V.G*., Rao V.S., Conrad W. D., Nagesh, H. N., Sreedhar Kumar, V., Divya Sridhar., Brust P., Murali Krishna M., Synthesis, Preliminary in vitro and in vivo pharmacological evaluation of4-{4-[2-(4-(2-substitutedquinoxalin-3-yl)piperazin-1-yl]ethyl) phenyl}thiazoles as atypical antipsychotic agents. Med. Chem. Res. 2013, 22 (4), 1660-1673.

11. Chandra Sekhar, K.V.G*., Rao. V.S., Tara Sasank, T. V. N. V., Nagesh, H.N., Suresh, N, Mahalakshmi Naidu, K., Suresh, A., Synthesis of 3,5-diarylisoxazoles under solvent-free conditions using iodobenzene diacetate. Chin. Chem. Lett. 2013, 24 (12), 1045 -1048.

10. Chandra Sekhar, K.V.G*., Vyas, D. R. K., H N Nagesh, Rao. V.S., Pharmacophore Hypothesis for Atypical Antipsychotics. Bull. Korean Chem. Soc. 2012, 33 (9), 2930-2936.

9. Chandra Sekhar, K.V.G*., Rao V.S., Kumar, D., Synthesis of Triazolo Quinoxalines as Antitubercular Agents. Bull. Korean Chem. Soc. 2011, 32 (8), 2657-2660.

8. Chandra Sekhar, K.V.G*., Rao V.S., Conrad W. D., Satish Reddy A., Brust P., Murali Krishna M. Design, Synthesis and Preliminary in vitro and in vivo pharmacological evaluation of 2-{4-[4-(Substituted thiazolyl)phenylethyl] piperazin-1-yl}-1,8-naphthyridine-3-carbonitriles as atypical antipsychotic agents. J. Enzyme Inhib. Med. Chem., 2011, 26 (4), 561-568.

7. Chandra Sekhar, K.V.G*., Rao V.S., Satish Reddy, A., Sunandini, R., Kumar Satuluri, V.S.A., Solvent Free Microwave Accelerated Synthesis of Heterocyclic Thiazolidin-4-ones as Antimicrobial and Antifungal Agents. Bull. Korean Chem. Soc. 2010, 31 (5), 1219-1222.

6. Chandra Sekhar, K.V.G*., Rao V.S., Murali Krishna Kumar M., Synthesis and preliminary screening of novel N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as potential atypical antipsychotic agents. J. Enzyme Inhib. Med. Chem., 2009, 24(3), 871-875.

5. Chandra Sekhar, K.V.G*., Rao V.S., Ravi Kumar Vyas, D., Murali Krishna Kumar M., Synthesis and preliminary pharmacological evaluation of N-2-(4-(4-(2-substitutedthiazol-4-yl) piperazin-1-yl)-2-oxoethyl)acetamides as novel atypical antipsychotic agents. Bioorg. Med. Chem. Lett., 2008, 18, 6054-6057.

4. Rao, V.S., Chandra Sekhar K.V.G*., Iodobenzene diacetate mediated solid-state synthesis of Heterocyclyl 1,3,4-oxadiazoles. Synthetic Commun., 2004, Vol.34 (12): 2153-2157.

3. Kumar, D., Chandra Sekhar, K.V.G., Dhillon, H., Rao, V.S., Varma, R.S., An expeditious synthesis of 1-aryl-4-methyl-1,2,4-triazolo [4,3-a] quinoxalines under solvent-free conditions using iodobenzene diacetate. Green Chem., 2004, Vol. 3: 156-157.

2. Sriram, D., Rao, V.S., Chandra Sekhar, K.V.G., Yogeeswari, P. Progress in the Research of Artemisinin and its analogues as antimalarials: An Update, Nat. Prod Res., 2004, Vol.18 (6): 503-527.

1. Rashmi P., Shaw A.K., Bhaduri A.P., Chandra Sekhar K. V. G., Anil S., Kishore K. S., Vineeta C., Ranjana S., Brahm S. S., Shalini A., Sudhir S., Higher Acyclic Nitrogen containing Deoxy sugar derivatives: A new lead in the generation of antimycobacterial chemotherapeutics. Bioorg. Med. Chem. Lett., 2002, 10, 1695-1702.

Papers in Conference / Symposium

B. Karankumar, Faheem, S. Murugesan, and K. V. G. Chandra Sekhar. Preliminary investigation of drug repurposing as a direction towards anti-Leishmanial drug discovery, International Conference on Drug Discovery (ICDD2020), BITS-Hyderabad, 29^th February-2^nd March 2020.
N. Adinarayana, S. Srinivarao, N. Sridhar, S. Murugesan, and K. V. G. Chandra Sekhar. Design, synthesis and biological evaluation of 2-aminobenzimidazoles as Quorum Sensing inhibitors in Pseudomonas aeruginosa. 26^th Indian Society for Chemists and Biologists Conference jointly organized with 5^th Nirma Institute of Pharmacy International Conference, Ahmadabad, 22^nd-24^th January 2020.
B. Karankumar, Faheem, G. Surajpyarelal, S. Murugesan, and K. V. G. Chandra Sekhar. In-silico target identification study of novel anti-leishmanial β-carboline agents. 26^th Indian Society for Chemists and Biologists Conference jointly organized with 5^th Nirma Institute of Pharmacy International Conference, Ahmadabad, 22^nd-24^th January 2020.
Faheem, G. Surajpyarelal, B. Karankumar, S. Murugesan, and K. V. G. Chandra Sekhar. In-silico target identification study of novel anti-leishmanial agents. 26^th Indian Society for Chemists and Biologists Conference jointly organized with 5^th Nirma Institute of Pharmacy International Conference, Ahmadabad, 22^nd-24^th January 2020.
K. V. G. Chandra Sekhar, S. Srinivasarao, S. Murugesan, and Naresh Kumar. Nitrogen based heterocycles as bacterial Quorum Sensing inhibitors in Pseudomonas aeruginosa. National Conference on New Frontiers in Chemistry - From Fundamentals to Applications (NFCFA2019), BITS, Goa, 20^th-22^nd December 2019. (Invited talk)
N. Adinarayana, S. Srinivarao, S. Murugesan, and K. V. G. Chandra Sekhar. 5,6-Dimethyl-2-aminobenzimidazoles as bacterial Quorum Sensing inhibitors in Pseudomonas aeruginosa. National Conference on New Frontiers in Chemistry - From Fundamentals to Applications (NFCFA2019), BITS, Goa, 20^th-22^nd December 2019.
K. Yogesh, C. Surendar, and K. V. G. Chandra Sekhar. 2-(3,4-dimethoxyphenyl)-6(1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridine analogues as antiproliferative agents. National Conference on New Frontiers in Chemistry - From Fundamentals to Applications (NFCFA2019), BITS, Goa, 20^th-22^nd December 2019.
N. Adinarayana, S. Srinivarao, H. N. Nagesh, S. Murugesan, and K. V. G. Chandra Sekhar. Deprotection of Methylene Nitrile Using Elemental Sulfur: Novel Strategy in Preparation of 1,2,3-triazoles. National Symposium on Convergence of Chemistry & Materials (CCM), BITS-Pilani Hyderabad campus, Hyderabad, 17-18^th December 2019.
S. Srinivasarao, G. Balaram, S. Murugesan and K.V.G. Chandra Sekhar. Design and synthesis of novel 1,2,3-triazole based quorum sensing inhibitors using molecular hybridization approach against Pseudomonas aeruginosa. 20^th Tetrahedron International Symposium - Bangkok, Thailand, 17-21^st June 2019.
K.V.G. Chandra Sekhar,S. Srinivas Rao,andS. Murugesan. Design, Synthesis and Biological Evaluation of triazole containing Salicylic acid as Quorum Sensing Inhibitors against P.aeruginosa. 6^th International Conference on Chemistry – Our Health, Our Future, organised by Indian Council of Chemists at Paris, France, June 06-08^th, 2019. (Invited talk).
N. Adinarayana, S. Murugesan and K.V.G. Chandra Sekhar, 3,4-Dihydroisoquinoline benzylidenes and 3,4-dihydroquinoline phenyl acetamides as potent Leishmanial inhibitors. 24th CRSI National Symposium in Chemistry, organized by CLRI and IIT Madras at Chennai, February 8-10th, 2019.
N. Adinarayana, S. Srinivas Rao, H. N. Nagesh, S. Murugesan and K.V.G. Chandra Sekhar, One-Pot Synthesis of 4-Substituted-2H-1,2,3-triazoles by Deprotection of Methylene Nitrile using elemental sulfur. Drug Discovery in India 2019 - Breakthrough Research in Medicinal Chemistry, organized by Selectbio Sciences India Pvt. Ltd., Mumbai, January 17-18^th, 2019.
S. Srinivas Rao, A. Suresh and K.V.G. Chandra Sekhar, N. Adinarayana, H. N. Nagesh, S. Murugesan and K.V.G. Chandra Sekhar, Seeking potential Quorum Sensing Inhibitors against Pseudomonas aeruginosa: Design, Synthesis and QSI activity of various triazoles. Drug Discovery in India 2019 - Breakthrough Research in Medicinal Chemistry, organized by Selectbio Sciences India Pvt. Ltd., Mumbai, January 17-18^th, 2019.
R.Rishi, A. Suresh and K.V.G. Chandra Sekhar, Design and synthesis of 1,2,3-triazolyl sulfonyl analogues as anti-tubercular agents. 24^th ISCB International Conference organized by Manipal University, Jaipur, January 11-13^th, 2018.
S. Srinivas Rao, A. Suresh and K.V.G. Chandra Sekhar, Design and synthesis of 1,2,3-triazolyl 9H-fluorenone analogues as anti-tubercular agents. National Symposium on Emerging Trends and Innovations in Pharmaceutical Science (ETIPS-2017) in chemistry, organized by JNTU Hyderabad, October 12-13, 2017. (Won the best paper award in oral section).
S. Srinivas Rao, A. Suresh and K.V.G. Chandra Sekhar, Design and synthesis of 1,2,3-triazolyl 9H-fluorenone analogues as anti-tubercular agents. National Symposium on Convergence of Chemistry & Materials (CCM-2017) in chemistry, organized by BITS-Pilani, Hyderabad campus, December 21-22, 2017.
C. Surendar, A. Suresh and K.V.G. Chandra Sekhar, Design and Synthesis of Indole, Oxindole and Isoxazole Derivatives as Quorum Sensing Inhibitors against P.aeruginosa. National Symposium on Convergence of Chemistry & Materials (CCM-2017) in chemistry, organized by BITS-Pilani, Hyderabad campus, December 21-22, 2017.
P. Ravikiran, R. Punna Rao, B. Mayank, K.V.G. Chandra Sekhar, Analysis of formaldehyde – a human carcinogen in drug substance using ultra-high performance liquid chromatograph. National Symposium on Convergence of Chemistry & Materials (CCM-2017) in chemistry, organized by BITS-Pilani, Hyderabad campus, December 21-22, 2017.
S. Srinivas Rao, A. Suresh, K. Mahalakshmi Naidu, Napiórkowska Agnieszka, Augustynowicz-Kopec Ewa, Sankaranarayanan Murugesan, Subhash Chander,Rangan Krishnan and K.V.G. Chandra Sekhar, Identification and development of 1,2,3-triazole derivatives of fused pyrazole-dihydropyridine as Mycobacterium tuberculosis Pantothenate synthetase inhibitors. 21^st National Symposium in Chemistry, organized by CRSI at Indian Institute of Chemical Technology, Hyderabad, July 13-16, 2017.
K.V.G. Chandra Sekhar,S. Srinivas Rao,K. Mahalakshmi Naidu,Shashidhar Nizalapur, Naresh Kumar, Design and Synthesis of Indole, Oxindole and Isoxazole Derivatives as Quorum Sensing Inhibitors against P.aeruginosa.5^th International Conference on Current Concepts in Chemistry, organised by Indian Council of Chemists at Bali, Indonesia, June 07-09^th, 2017. (Invited talk).
K.V.G. Chandra Sekhar,Nitrogen based Heterocycles as anti-tubercular agents, National Conference on “Organic Chemistry in Sustainable Development: Recent Advances and Future Challenges (OCSD-2016) organized by Chemistry department, BITS Pilani, August 29-30, 2016. (Invited talk).
C. Surendar, A. Suresh and K. V. G. Chandra Sekhar, Design and synthesis of novel fluconazole triazole analogues as anticancer agents. National Conference on “Organic Chemistry in Sustainable Development: Recent Advances and Future Challenges (OCSD-2016) organized by Chemistry department, BITS Pilani, August 29-30, 2016.
S. Srinivas Rao, K. Mahalakshmi Naidu, A. Suresh, K.V.G. Chandra Sekhar. Synthesis and biological activity of 6-(piperazin-1-yl)phenanthridine sulphonamide derivatives as potent anti-tubercular agents. International Symposium on Bioorganic Chemistry (ISBOC-10), Indian Institute of Science Education and Research, Pune, January 11-15^th, 2015.
A.Suresh, K.Mahalakshmi Naidu, S. Srinivas Rao, K.V.G.Chandra Sekhar. Synthesis and characterization of new tetrazole derivatives as anti-tubercular agents. International Symposium on Bioorganic Chemistry(ISBOC-10), Indian Institute of Science Education and Research, Pune, January 11-15^th, 2015.
N. Suresh, A. Kumar, K. Parang,M. Alvala, K.V.G. ChandraSekhar. Synthesis and anticancer evaluation of novel ciprofloxacin analogues. International Conference on Innovations in Chemical Research and Applied Chemical Sciences at Smt. Chandibai Himathmal Mansukhani College, Ulhasnagar-3, Mumbai, January 12-13^th, 2015. (Won the best paper award in poster section).
K. Mahalakshmi Naidu, H.N. Nagesh, S. Srinivasarao, A. Suresh, N.Suresh, D. Sriram, K.V.G. Chandra Sekhar, Design, synthesis and biological evaluation of novel Phenanthridine amide analogues as potent anti-tubercular agents. 13^th Eurasia Conference on Chemical Sciences at Indian Institute of Science, Bangalore, India, December 14 - 18^th 2014.
H.N. Nagesh, A. Suresh, D. Sriram, P. Yogeeswari, K.V.G. Chandra Sekhar. A new hybrid approach for design, synthesis and evaluation of substituted phenethylthiazole derivatives as antitubercular agents. 15^th Tetrahedron Symposium - Asian Edition on Challenges in Bioorganic and Organic Medicinal Chemistry organised by Elsevier at Singapore Expo, Singapore, October 28 -31^st, 2014.
K.V.G. Chandra Sekhar, A. Suresh, H.N.Nagesh, N.Suresh, K.Mahalakshmi Naidu, D.Sriram, P.Yogeeswari. Design, Synthesis and anti-tubercular activity of various Phenanthridine analogues. 3rd International Conference on chemistry for sustainable development: Indian perspective, organised by Indian Council of Chemists at Dubai, United Arab Emirates, June 10-14^th, 2014.
H.N.Nagesh, K.Mahalakshmi Naidu, A. Suresh, J.Subbalakshimi, D.Sriram, P.Yogeeswari, K.V.G. Chandra Sekhar. Design, synthesis and anti-tubercular evaluation of novel benzo[d]isoxazole hybrid analogues. International conference on drugs for the Future: Infectious Diseases, Antimicrobial Drug Discovery: Challenges and perspectives DFID-2014, NIPER, Hyderabad, March 27-28^th, 2014.
K.Mahalakshmi Naidu, A. Suresh, N.Suresh, H.N.Nagesh, K.V.G. Chandra Sekhar. Design, synthesis and in vitro antifungal evaluation of novel ciprofloxacin derivatives. 5^th National seminar on Bioinformatics, Sri Venkateshwara Institute of Medical Sciences, Tirupati, February 14-15^th , 2014. (Won the best paper award in poster section).
K.Mahalakshmi Naidu, H.N.Nagesh, N.Suresh, A. Suresh, K.V.G. Chandra Sekhar, Synthesis and evaluation of phenanthridine analogues as anti-tubercular agents. 16^th CRSI Symposium in Chemistry, IIT Bombay, February 7 -9^th, 2014.
A.Suresh, H.N.Nagesh, N.Suresh, K.Mahalakshmi Naidu, D.Sriram, P.Yogeeswari, K.V.G.Chandra Sekhar. Synthesis and anti-tubercular activity of 6-(4-substitutedpiperazin-1-yl) phenanthridine analogues. International conference on Chemical Biology, Disease mechanisms and Therapeutics (IICB-2014), Indian Institute of Chemical Technology, Hyderabad, February 6-8^th, 2014.
N.Suresh, H.N.Nagesh, K.Mahalaxmi Naidu, A. Suresh, K.V.G. Chandra Sekhar, K. Parang, Design and synthesis of 1-cyclopropyl-6-fluoro-4-oxo-7-{4-substituted piperazin-1-yl}-1, 4-dihydro quinoline-3-carboxylic acid derivatives asAntiproliferative agents. National Poster- II Symposium on Advances in Organic / Medicinal Chemistry (AOMC-2013), Krishna University, Vijayawada, December 21^st, 2013.
N.Suresh, H.N.Nagesh, K.Mahalaxmi Naidu, Inshad Ali Khan, K.V.G. Chandra Sekhar, Design and synthesis of 1-cyclopropyl-6-fluoro-4-oxo-7-{4-substituted piperazin-1-yl}-1, 4-dihydro quinoline-3-carboxylic acid derivatives as Anti-tubercular agents, 2nd UK-India MedChem Congress, IICT Hyderabad, March 22-23^rd, 2013.
H.N. Nagesh, K. Mahalakshmi Naidu, N. Suresh, K.V.G. Chandra Sekhar, Design and synthesis of novel phenanthridine derivatives as anticancer agents, 19^th ISCB International Conference (ISCBC – 2013), Mohanlal Sukhadia University Udaipur, March 2-5^th, 2013.
K.Mahalakshmi Naidu, H.N. Nagesh, N.Suresh, K.V.G. Chandra Sekhar, Synthesis Of Benzisoxazolylpiperazines as dopamine D2 antagonists, CTDDR 2013 : 5^th International Conference on Drug Development and Orphan/Neglected Diseases, CDRI Lucknow, February 26-28^th, 2013.
N.Suresh, H.N.Nagesh, K.Mahalaxmi Naidu, K.V.G. Chandra Sekhar, Design and synthesis of 1, 3-disubstituted 5-(2-(4-substituted piperazine-1-yl) acetyl) indoline-2-one derivatives as anti-cancer agents, 15^th CRSI National Symposium in Chemistry, Banaras Hindu University – Varanasi, February 1-3^rd, 2013.
N.Suresh, H.N.Nagesh, K.Mahalakshmi Naidu, K.V.G. Chandra Sekhar, Design and Synthesis of 1-cyclopropyl-6-fluoro-4-oxo-7-{4-substituted piperazin-1-yl}-1,4-dihydro quinoline-3-carboxylic acid derivatives as anti-tumor agents, 6^th Midyear CRSI Symposium in Chemistry, CDRI Lucknow, July 21-22^nd, 2012.
H.N. Nagesh, N.Suresh, K. Mahalakshmi Naidu, V.S. Rao, K.V.G. Chandra Sekhar, Synthesis of Phenanthridinyl piperazines as novel Dopamine D2 antagonists. 14^th CRSI National Symposium on Chemistry, CSIR-NIIST, Thiruvananthapuram, February 3-5^th, 2012.
K V G Chandra Sekhar, V S Rao, T V N V Tara Sasank, V Sreedhar Kumar, An Expeditious Synthesis of 3,5-Diarylisoxazoles under solvent-free conditions using Iodobenzene diacetate. 13^th CRSI National Symposium on Chemistry, NISERKIIT University, Bhubaneshwar, February 4-6^th, 2011.
K V G Chandra Sekhar, V S Rao, V Sreedhar Kumar, Design, Synthesis and Pharmacological Evaluation of substituted quinoxalines as Atypical Antipsychotics. 62^nd Indian Pharmacutical Congress, Manipal, December 17-19^th, 2010, p.B239.
V Sreedhar, V S Rao, W Deuther-Conrad, P Brust, K V G Chandra Sekhar, Design, Synthesis and Preliminary in vitro and in vivo Pharmacological Evaluation of quinoxalinylthiazoles as Atypical Antipsychotic Agents, 5th Midyear CRSI Symposium in chemistry, Trivendrum, July 23-24^th, 2010.
K V G Chandra Sekhar, V S Rao, Winnie Deuther-Conrad, Peter Brust, Design, Synthesis and Preliminary in vitro and in vivo Pharmacological Evaluation of 2-{4-[4-(substitutedthiazolyl)phenylethyl]piperazin-1-yl}-1,8-naphthyridine-3-carbonitriles as Atypical Antipsychotic Agents. 12th CRSI National Symposium in Chemistry, Indian Institute of Chemical Technology, Hyderabad, India, February 4-7^th, 2010.
K.V.G. Chandra Sekhar, V. S. Rao, M. Murali Krishna, R. Mahesh, Synthesis of N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as novel D2 Antagonists: International conference on the interface of chemistry – biology in Biomedical Research, BITS, Pilani, February 22-24^th, 2008, p212.
K.V.G. Chandra Sekhar, V.S. Rao and D. Ravi Kumar Vyas, Pharmacophore Hypothesis for Atypical Antipsychotics: International conference on the interface of chemistry – biology in Biomedical Research, BITS, Pilani, February 22-24^th, 2008, p202.
K. V. G. Chandra Sekhar, V. S. Rao, Anisha Thomas, A. Satish Reddy, R. Sunandini, V.S.A. Kumar Satuluri, Solvent Free Microwave Assisted Synthesis of 3-(2-methylquinoxalin-3-yl)-2-(substitutedphenyl)thiazolidin-4-ones: International conference on the interface of chemistry – biology in Biomedical Research, BITS, Pilani, February 22-24^th, 2008, p125.
Satish, A., K V G Chandra Sekhar, A.Ashok Kumar, V S Rao, Process development of chloroethyl phenylthiazole derivatives – intermediates of novel potential atypical antipsychotics agents: National Symposium on Challenges In Drug Discovery Research: Networking Oppurtunities Between Academia & Industries, BITS, Pilani. April 3-4^th, 2006, p 44.
A.Ashok Kumar, V S Rao, K V G Chandra Sekhar, Vipul Jain. A Cost-effective synthesis of 9-Fluorenone oxime using conventional and microwave approaches: National Symposium on Challenges In Drug Discovery Research: Networking Oppurtunities Between Academia & Industries, BITS, Pilani. April 3-4^th, 2006, p 46.
V.S.Rao, K.V.G.Chandra Sekhar, Divya Sridhar and Dalip Kumar, Microwave Assisted Synthesis of Isonicotinoyl Hydrazones. International Symposium on Recent Advances In Drug Design & Delivary Systems, BITS, Pilani, February 26-27^th, 2005, p38-39.
V.S.Rao, K.V.G.Chandra Sekhar, A.Ashok Kumar and Dalip Kumar, Synthesis of 1-aryl-4-methyl-1,2,4-triazolo[4,3-a]quinoxalines as Antitubercular Agents: International Symposium on Recent Advances In Drug Design & Delivary Systems, BITS, Pilani, February 26-27^th, 2005, p33-34.
K.V.G. Chandra Sekhar, V.S. Rao, Harmeet Dhillon, A. Ashok kumar, Iodobenzene diacetate mediated synthesis of Triazolo Quinoxalines: National Conference for Pharmacy Students, Current Research in Academic Institutions, Shri Vishnu College of Pharmacy, Bhimavaram, March, 7-8^th, 2003, p1.

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