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Title of the project: Design and synthesis of inhibitors of Mycobacterium tuberculosis sigma
factor-RNAP protein-protein interaction as potential antimycobacterial agents
Funding agency: ICMR
Duration: 3 years
Amount (lakhs): 41.11
PI and Co-I: Sandeep Sundriyal (PI); Gopal Balasubramanian (Co-I)
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Title of the project: Computational design, synthesis and screening of non-hydroxamate
lipophilic DXR inhibitors as potential antibacterial/antimalarial/anti-TB agents
Funding agency: SERB
Duration: 3 years
Amount (lakhs): 30.46
PI and Co-I: Sandeep Sundriyal (PI); Mukti N Mishra (Co-I)
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Title of the project: Targeting chromatin modifiers- Jumonji Histone Demethylases in tumor
cells surviving acute drug stress: an in vitro and in vivo study
Funding agency: ICMR
Duration: 3 years
Amount (lakhs): 37.10
PI and Co-I: Rajdeep Chowdhary (PI); Sandeep Sundriyal (Co-I)
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Title of the project: Klotho regulation as a novel therapeutic strategy against acute kidney
injury-diabetes comorbidity: Impact of epigenetic driven and epigenetic independent
reactivation of endogenous Klotho expression.
Funding agency: SERB
Duration: 3 years
Amount (lakhs): 50.33
PI and Co-I: Gaikwad Anil Bhanudas (PI)
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Title of the project: Exploring the mechanism(s) of gut microbiota link to Parkinson Disease
pathology and its reversal based on fibroblast growth factor 21 gene delivery through lentivirus
system.
Funding agency: ICMR
Duration: 3 years
Amount (lakhs): 42.56
PI and Co-I: Rajeev Taliyan (PI); Sunil k Dubey, Amit Goyal (Co-I)
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Title of the project: Exploring the effects of polyamine and associated metabolic regulation of
hypothalamic GnRH-GnIH synthesis and release during ageing in BALB/cJ mice.
Funding agency: SERB
Duration: 3 years
Amount (lakhs): 34.35
PI and Co-I: Dr. Arnab Banerjee, BITS Goa (PI); Rajeev Taliyan (Co-I)
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Title of the project: Peptide-tethered multifunctional cationic nanocomplexes for delivery of IL-
1 receptor antagonist for treatment of type 2 diabetes mellitus
Funding agency: SERB
Duration: 3 years
Amount (lakhs): 40.46
PI and Co-I: Anupama Mittal (PI); Deepak Chitkara (Co-I)
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Title of the project: Development of a complete skin substitute by autologous cell grafting using
an in-situ forming bioactive scaffold for burn wound healing
Funding agency: DBT
Duration: 1.5 years
Amount (lakhs): 25
PI and Co-I: Aniruddha Roy (PI); Archana Singh (IGIB) (Co-I)
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Title of the project: Develop of novel anti-leishmanial analogues loaded with novel nano-
formulations
Funding agency: DBT
Duration: 3 years
Amount (lakhs): 60
PI and Co-I: S. Murugesan (PI); K.V.G.Chandrasekhar (Co-I)
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Title of the project: Design, Synthesis, Biological Evaluation and Molecular Modelling Studies
of Indolyl Oxoacetamide Quinazolinone Based Hybrid Analogs as Potential Pancreatic Lipase
Inhibitors for Obesity Treatment
Funding agency: DST
Duration: 3 years
Amount (lakhs): 35
PI and Co-I: Atish T Paul (PI)
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Title of the project: Gel-based composite formulation containing asiaticoside and neurotensin
for rapid healing of diabetic wounds
Funding agency: ICMR
Duration: 3 years
Amount (lakhs): 25.67
PI and Co-I: Anupama Mittal (PI); Deepak Chitkara (Co-I)
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Title of the project: Self-assembling, pH-sensitive temozolomide conjugate nanomedicine for
treatment of glioblastoma multiforme
Funding agency: ICMR
Duration: 3 years
Amount (lakhs): 25.27
PI and Co-I: Deepak Chitkara(PI); Anupama Mittal(Co-I)
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Title of the project: cRGD decorated lipo-polymeric nanoplexes of CRISPR/Cas9
ribonucleoprotein (RNP) for the management of retinal dystrophic conditions
Funding agency: DBT
Duration: 3 years
Amount (lakhs): 125.214
PI and Co-I: Deepak Chitkara(PI); Anupama Mittal (Co-I)
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Title of the project: Discovery of myeloperoxidase (MPO) inhibitors for the potential treatment
of critically ill COVID-19 patients with cytokine storm.
Funding agency: IIT Delhi
Duration: 3 years
Amount (lakhs): 10
PI and Co-I: Vaibhav A. Dixit (PI); Atish Paul (Co-I)
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Title of the project: Health TB project: Design and synthesis of Mycobacterium UDG inhibitors
Funding agency: The Office of PSA
Duration: 2 years
Amount (lakhs): 10
PI: Sandeep Sundriyal
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Title of the project: Development and evaluation of lipid based nanoparticles of Quinapyramine
and Isometamidium chloride for treatment of trypanosomiasis in camels
Funding agency: DBT
Duration: 3 years
Amount (lakhs): 44.72
PI and Co-I: Anil Jindal (PI); Samar Ghorui (NRCC, Bikaner), Atish Paul (Co-I)
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Title of the project: Rod-shaped polymeric nanoparticles for targeted delivery of artemisinin-
derivatives to plasmodium-infected erythrocytes for improved intravenous therapy of cerebral
malaria
Funding agency: SERB
Duration: 3 years
Amount (lakhs): 44.30
PI: Anil Jindal (PI)
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Title of the project: Peptide-decorated pH-sensitive nano-conjugate hybrid micelles for co-
delivery of temozolamide and an autophagy inducer, rapamycin, for treatment of glioblastoma
multiforme.
Funding agency: DBT
Duration: 3 years
Amount (lakhs): 41.94
PI and Co-I: Deepak Chitkara (PI); Gaikwad Anil Bhanudas (Co-I)
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Title of the project: Actively targeted nano-formulations for co-delivery of a taxane and
antioxidant molecule, alpha lipoic acid, for treating breast cancer.
Funding agency: DST-Rajasthan
Duration: 3 years
Amount (lakhs): 11.13
PI: Deepak Chitkara (PI);
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Title of the project: Exploiting the electron transfer (ET) parameters for the prediction of
selectivities in Cytochrome P450 (CYP450) catalyzed biotransformations of industrial
importance.
Funding agency: NSM, DST, New Delhi
Duration: 2 years
Amount (lakhs): 19.16
PI and Co-I: Vaibhav A. Dixit (PI); Priyanka Bajaj (Co-I)
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