Enzymes are evolved by Nature to catalyze in vivo biochemical reactions. These biocatalysts have a great potential to complement many useful unnatural chemical reactions. However enzymes often need to be engineered to achieve high stability, selectivity and catalytic efficiency to make them suitable for practical application.  

 

We are interested in engineering enzymes by rational protein design, semi-rational or directed molecular evolution to prepare tailor-made enzymes suitable for the synthesis of fine chemicals, stereoselective products, chiral pharmaceutical intermediates, in the application of biofuel, bioenergy, detoxification of toxic organic compounds and other industrial applications