More than 60 research publication 
Google scholar link Publications from last few years | |
Triazolo-linked benzimidazoles as tubulin polymerization inhibitors and DNA intercalators: Design, synthesis, cytotoxicity, and docking studies. Kritika Laxmikeshav, Mone Sayali, Geetanjali Devabattula, Durgesh G. Valapil, Ashutosh Mahale, Pravesh Sharma, Joel George, Regur Phanindranath, Chandraiah Godugu, Onkar P. Kulkarni, Narayana Nagesh, Nagula Shankaraiah.Archiv der Pharmazie | 2023 |
| Solid-state emitting twisted π-conjugate as AIE-active DSE-gen: in vitro anticancer properties against FaDu and 4T1 with biocompatibility and bioimaging.Bhuin S, Sharma P, Chakraborty P, Kulkarni OP, Chakravarty M. J Mater Chem B. 2022 Dec 22;11(1):188-203. | 2023 |
Benzimidazole based bis-carboxamide derivatives as promising cytotoxic agents: Design, synthesis, in silico and tubulin polymerization inhibition. K Laxmikeshav, P Sharma, M Palepu, P Sharma, A Mahale, J George et al. Journal of Molecular Structure 1271, 134078
| 2023 |
A modular approach to fluorescent probes: Extending the scope of β-carboline scaffold to selective fluoride sensing and its application in the visualisation of fluoride-induced ROS AK Shukla, A Mahale, OP Kulkarni, A Bhattacharya. Journal of Photochemistry and Photobiology A: Chemistry 437, 114453
| 2023 |
N-2-Hydroxypropylmethacrylamide-Polycaprolactone Polymeric Micelles in Co-delivery of Proteasome Inhibitor and Polyphenol: Exploration of Synergism or Antagonism. Rani S, Sahoo RK, Kumar V, Chaurasiya A, Kulkarni O, Mahale A, Katke S, Kuche K, Yadav V, Jain S, Nakhate KT, Ajazuddin, Gupta U. Mol Pharm. 2023 Jan 2;20(1):524-544
| 2023 |
Selective inhibition of PKR by C16 accelerates diabetic wound healing by inhibiting NALP3 expression in mice. Karnam K, Sedmaki K, Sharma P, Venuganti VVK, Kulkarni OP. Inflamm Res. 2022 Nov 23
| 2022 |
HDAC6 inhibition attenuates renal injury by reducing IL-1β secretion and RIP kinase mediated necroptosis in acute oxalate nephropathy. K Sedmaki, K Karnam, P Sharma, A Mahale, G Routholla, B Ghosh, Kulkarni OP. International Immunopharmacology 110, 108919
| 2022 |
HDAC5 RNA interference ameliorates acute renal injury by upregulating KLF2 and inhibiting NALP3 expression in a mouse model of oxalate nephropathy. Sharma P, Karnam K, Mahale A, Sedmaki K, Krishna Venuganti V, Kulkarni OP. Int Immunopharmacol. 2022 Nov;112:109264
| 2022 |
Inhibition of Autotaxin Ameliorates LPA-Mediated Neuroinflammation and Alleviates Neurological Dysfunction in Acute Hepatic Encephalopathy. Roy S, Chakrabarti M, Dasgupta H, Mahale A, Tripathi S, Sharma V, Banerjee M, Kulkarni OP. ACS Chem Neurosci. 2022 Oct 5;13(19):2829-2841
| 2022 |
RIPK3-MLKL signaling activates mitochondrial CaMKII and drives intrarenal extracellular matrix production during CKD. Srivastava A, Tomar B, Sharma P, Kumari S, Prakash S, Rath SK, Kulkarni OP, Gupta SK, Mulay SR. Matrix Biol. 2022 Sep;112:72-89.
| 2022 |
Pyrrole-pyridine chelating motif on the β-carboline skeleton: Selective Zn2+ sensing via inhibition of ESIPT, Adarash Kumar Shukla, Rituparna Hazra, Pravesh Sharma, Subit Kumar Saha, Durba Roy, Onkar Prakash Kulkarni, Anupam Bhattacharya, Dyes and Pigments, Volume 202, June 2022, 110238
| 2022 |
Estrogenic Activity of Tetrazole Derivatives Bearing Bisphenol Structures: Computational Studies, Synthesis, and In Vitro Assessment. Gadgoli UB, Y C SK, Kumar D, Pai MM, Pulya S, Ghosh B, Kulkarni OP. J Chem Inf Model. 2022 Feb 28;62(4):854-873
| 2022 |
Cyclo(Val-Pro) and Cyclo(Leu-Hydroxy-Pro) from Pseudomonas sp. (ABS-36) alleviates acute and chronic renal injury under in vitro and in vivo models (Ischemic reperfusion and unilateral ureter obstruction). Kirti Hira, Pravesh Sharma, Ashutosh Mahale, Onkar Kulkarni, Sajeli Begum A. Int Immunopharmacol. 2022 Feb;103:108494
| 2022 |
| PT3: A Novel Benzamide Class Histone Deacetylase 3 Inhibitor Improves Learning and Memory in Novel Object Recognition Mouse Model. Pulya S, Mahale A, Bobde Y, Routholla G, Patel T, Swati, Biswas S, Sharma V, Kulkarni OP, Ghosh B. ACS Chem Neurosci. 2021 Mar 3;12(5):883-892 | 2021 |
| Halodule pinifolia (Seagrass) attenuated lipopolysaccharide-, carrageenan-, and crystal-induced secretion of pro-inflammatory cytokines: mechanism and chemistry. Begum, S.A., Hira, K., Pal, P.P., Samrun N, Kulkarni O.P., Jeyapragash D., Shaik A.B., Araya H, Yoshinori F. Inflammopharmacol (2020). https://doi.org/10.1007/s10787-020-00747-x | 2020 |
| HDAC6 inhibitor accelerates wound healing by inhibiting tubulin mediated IL-1β secretion in diabetic mice. Karnam K, Sedmaki K, Sharma P, Routholla G, Goli S, Ghosh B, Venuganti VVK, Kulkarni OP. Biochim Biophys Acta Mol Basis Dis. 2020 Nov 1;1866(11):165903. | 2020 |
| New synthetic coumarinolignans as attenuators of pro-inflammatory cytokines in LPS-induced sepsis and carrageenan-induced paw oedema models. Kumar SS, Hira K, Begum Ahil S, Kulkarni OP, Araya H, Fujimoto Y. Inflammopharmacology. 2020 Apr 30. doi: 10.1007/s10787-020-00710-w. | 2020 |
| l-Proline-based-cyclic dipeptides from Pseudomonas sp. (ABS-36) inhibit pro-inflammatory cytokines and alleviate crystal-induced renal injury in mice. Begum Ahil S, Hira K, Shaik AB, Pal PP, Kulkarni OP, Araya H, Fujimoto Y. Int Immunopharmacol. 2019 Aug;73:395-404. | 2019 |
Effective melanoma cancer suppression by iontophoretic co-delivery of STAT3 siRNA and imatinib using gold nanoparticles. Labala S, Jose A, Chawla SR, Khan MS, Bhatnagar S, Kulkarni OP, Venuganti VVK. Int J Pharm. 2017 Jun 20;525(2):407-417.
| 2017 |
Shubhmita Bhatnagar, Sumeet R. Chawla, Onkar P. Kulkarni, Venkata Vamsi Krishna Venuganti. Zein microneedles for transcutaneous vaccine delivery: fabrication, characterization and in-vivo evaluation using ovalbumin as model antigen. ACS Omega 2, 1321-1332 (2017)
| 2017 |
Cellular and Molecular Mechanisms of Autoimmunity and Lupus Nephritis. Devarapu SK, Lorenz G, Kulkarni OP, Anders HJ, Mulay SR. Int Rev Cell Mol Biol. 2017;332:43-154
| 2017 |
The innate immune system in human systemic lupus erythematosus. Weidenbusch M, Kulkarni OP, Anders HJ. Clin Sci (Lond). 2017 Apr 25;131(8):625-634.
| 2017 |
| The Immune System in Tissue Environments Regaining Homeostasis After Injury. Is “Inflammation” Always Inflammation?" by Onkar P. Kulkarni, Julia Lichtnekert, Hans-Joachim Anders and Shrikant R. Mulay. Mediators Inflamm. 2016;2016:2856213 | 2016 |
| Dual blockade of the pro-inflammatory chemokine CCL2 and the homeostatic chemokine CXCL12 is as effective as high dose cyclophosphamide in murine proliferative lupus nephritis. Devarapu SK, Vr SK, Rupanagudi KV, Kulkarni OP, Eulberg D, Klussmann S, Anders HJ. Clin Immunol. 2016 Jul 5. pii: S1521-6616(16)30155-3. doi: 10.1016/j.clim.2016.07.003 | 2016 |
Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD-Related Systemic Inflammation. Andersen K, Kesper MS, Marschner JA, Konrad L, Ryu M, Kumar Vr S, Kulkarni OP, Mulay SR, Romoli S, Demleitner J, Schiller P, Dietrich A, Müller S, Gross O, Ruscheweyh HJ, Huson DH, Stecher B, Anders HJ. J Am Soc Nephrol. 2016 May 5. pii: ASN.2015111285. | 2016 |
| Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis. Mulay SR, Desai J, Kumar SV, Eberhard JN, Thomasova D, Romoli S, Grigorescu M, Kulkarni OP, Popper B, Vielhauer V, Zuchtriegel G, Reichel C, Bräsen JH, Romagnani P, Bilyy R, Munoz LE, Herrmann M, Liapis H, Krautwald S, Linkermann A, Anders HJ. Nat Commun. 2016 Jan 28;7:10274. doi: 10.1038/ncomms10274. | 2016 |
| NLRP3 and ASC suppress lupus-like autoimmunity by driving the immunosuppressive effects of TGF-β receptor signalling. Lech M, Lorenz G, Kulkarni OP, Grosser MO, Stigrot N, Darisipudi MN, Günthner R, Wintergerst MW, Anz D, Susanti HE, Anders HJ. Ann Rheum Dis. 2015 Dec;74(12):2224-35 | 2015 |
| Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN. Kumar SV, Kulkarni OP, Mulay SR, Darisipudi MN, Romoli S, Thomasova D, Scherbaum CR, Hohenstein B, Hugo C, Müller S, Liapis H, Anders HJ. J Am Soc Nephrol. 2015 Oct;26(10):2399-413. | 2015 |
| Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming. Rupanagudi KV, Kulkarni OP, Lichtnekert J, Darisipudi MN, Mulay SR, Schott B, Gruner S, Haap W, Hartmann G, Anders HJ. Ann Rheum Dis. 2015 Feb;74(2):452-63. | 2015 |
| Toll-like receptor 4-induced IL-22 accelerates kidney regeneration. Kulkarni OP, Hartter I, Mulay SR, Hagemann J, Darisipudi MN, Kumar Vr S, Romoli S, Thomasova D, Ryu M, Kobold S, Anders HJ. J Am Soc Nephrol. 2014 May;25(5):978-89. | 2014 |
Effect of combination treatment of S-amlodipine with peroxisome proliferator-activated receptor agonists on metabolic and cardiovascular parameters in Zucker fa/fa rats. Singh B, Sangle GV, Murugan J, Umrani R, Roy S, Kulkarni O, Semwal A, Unnikrishnan M, Jain M. Diabetol Metab Syndr. 2014 Mar 28;6(1):45.
| 2014 |
| The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration. Migliorini A, Angelotti ML, Mulay SR, Kulkarni OO, Demleitner J, Dietrich A, Sagrinati C, Ballerini L, Peired A, Shankland SJ, Liapis H, Romagnani P, Anders HJ. Am J Pathol. 2013 Aug;183(2):431-40. | 2013 |
| Podocyte loss involves MDM2-driven mitotic catastrophe. Mulay SR, Thomasova D, Ryu M, Kulkarni OP, Migliorini A, Bruns H, Gröbmayr R, Lazzeri E, Lasagni L, Liapis H, Romagnani P, Anders HJ. J Pathol. 2013 Jul;230(3):322-35. | 2013 |
| Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury. Lech M, Römmele C, Gröbmayr R, Eka Susanti H, Kulkarni OP, Wang S, Gröne HJ, Uhl B, Reichel C, Krombach F, Garlanda C, Mantovani A, Anders HJ. Kidney Int. 2013 Apr;83(4):647-61. | 2013 |
| Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion. Mulay SR, Kulkarni OP, Rupanagudi KV, Migliorini A, Darisipudi MN, Vilaysane A, Muruve D, Shi Y, Munro F, Liapis H, Anders HJ. J Clin Invest. 2013 Jan;123(1):236-46. | 2013 |
| Lupus nephritis. How latest insights into its pathogenesis promote novel therapies. Kulkarni OP, Anders HJ. Curr Opin Rheumatol. 2012 Sep;24(5):457-65. | 2012 |
| Recombinant chaperonin 10 suppresses cutaneous lupus and lupus nephritis in MRL-(Fas)lpr mice. Kulkarni OP, Ryu M, Kantner C, Sárdy M, Naylor D, Lambert D, Brown R, Anders HJ. Nephrol Dial Transplant. 2012 Apr;27(4):1358-67. | 2012 |
| Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus. Lech M, Kantner C, Kulkarni OP, Ryu M, Vlasova E, Heesemann J, Anz D, Endres S, Kobayashi KS, Flavell RA, Martin J, Anders HJ. Ann Rheum Dis. 2011 Dec;70(12):2207-17. | 2011 |
| Mdm2 promotes systemic lupus erythematosus and lupus nephritis. Allam R, Sayyed SG, Kulkarni OP, Lichtnekert J, Anders HJ. J Am Soc Nephrol. 2011 Nov;22(11):2016-27. | 2011 |
| Activated protein C attenuates systemic lupus erythematosus and lupus nephritis in MRL-Fas(lpr) mice. Lichtnekert J, Rupanagudi KV, Kulkarni OP, Darisipudi MN, Allam R, Anders HJ. J Immunol. 2011 Sep 15;187(6):3413-21. | 2011 |
| IRF4 deficiency abrogates lupus nephritis despite enhancing systemic cytokine production. Lech M, Weidenbusch M, Kulkarni OP, Ryu M, Darisipudi MN, Susanti HE, Mittruecker HW, Mak TW, Anders HJ. J Am Soc Nephrol. 2011 Aug;22(8):1443-52. | 2011 |
| Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney disease. Darisipudi MN, Kulkarni OP, Sayyed SG, Ryu M, Migliorini A, Sagrinati C, Parente E, Vater A, Eulberg D, Klussmann S, Romagnani P, Anders HJ. Am J Pathol. 2011 Jul;179(1):116-24. | 2011 |
| An orally active chemokine receptor CCR2 antagonist prevents glomerulosclerosis and renal failure in type 2 diabetes. Sayyed SG, Ryu M, Kulkarni OP, Schmid H, Lichtnekert J, Grüner S, Green L, Mattei P, Hartmann G, Anders HJ. Kidney Int. 2011 Jul;80(1):68-78. | 2011 |
| Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss. Ryu M, Kulkarni OP, Radomska E, Miosge N, Gross O, Anders HJ. Kidney Int. 2011 Jan;79(2):189-98. | 2011 |
| Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1. Lichtnekert J, Kulkarni OP, Mulay SR, Rupanagudi KV, Ryu M, Allam R, Vielhauer V, Muruve D, Lindenmeyer MT, Cohen CD, Anders HJ. PLoS One. 2011;6(10):e26778. | 2011 |
| Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. Lech M, Römmele C, Kulkarni OP, Susanti HE, Migliorini A, Garlanda C, Mantovani A, Anders HJ. PLoS One. 2011;6(5):e20118. | 2011 |
| 4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice. Kulkarni OP, Sayyed SG, Kantner C, Ryu M, Schnurr M, Sárdy M, Leban J, Jankowsky R, Ammendola A, Doblhofer R, Anders HJ. Am J Pathol. 2010 Jun;176(6):2840-7. | 2010 |
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