BITS Pilani

  • Page last updated on Tuesday, April 25, 2023

Sponsored Projects

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Sponsored Projects

Extramural Funding

Name of Project

Duration

Funding Agency

Budget

 

Major Grant

 

Structure-function relationship in lupin leghemoglobin pertinent to a new, ubiquitous class of heme proteins with yet unknown physiological function

 

2008-2011

 

DBT

 

78.268 Lakhs

Spectroscopic Characterization / Screening of Hemoglobin Disorders

2008-2011

DBT

23.02 Lakhs

Structure-function relationship in Dopamine Beta hydroxylase and neuroglobin (as Co-Coordinator; part of COE grant to Prof. B.K. Thelma;)

2008-2013

DBT

32.50 Lakhs

Characterizing Novel Globins Across Species and Deciphering their Stress Response and Interacting Partners: An Integrated, Holistic Approach for Function Elucidation (as Coordinator)

 

2009-2012

 

DU-DST

PURSE

 

252.885 Lakhs (My share: 41.52 Lakhs)

Functional properties of plant hemoglobins embedded in nanoporous silica gels

2008-2009

University of Parma, Italy

Student exchange programme

Mossbauer Spectroscopy of Mammalian and other Novel Hemoglobins

2007-2012

Research Collaboration with Ural State Technical University-UPI, Ekaterinburg, Russia

Student exchange programme and academic collaboration

Development of potent small molecule inhibitors against dopamine beta-hydroxylase to combat cardiovascular diseases (as Coordinator; co-PI Prof. N.G. Ramesh, IIT, Delhi)

15.06.2015 to 14.06.2018

 

DBT

Rs.51,65,500 (Total budget Rs.78,90,300)

 

Systems biology of complex diseases: From genetic findings to lead molecule development for Rheumatoid arthritis- Centre of Excellence in Genome Sciences and Predictive Medicine (Phase II) (as co-Coordinator;Coordinator Prof. B.K. Thelma)

21.12.2015 to 20.12.2021

 

DBT

 

Rs.60.62 Lakhs

Screening Lead Molecules Identified by Structurebased Rational Drug Design Methods against Cytochrome b5 Reductase 3 and Dopamine Beta Hydroxylase in Spontaneously Hypertensive Rat Models for Antihypertensive Effects (as Coordinator;co-PI- Dr. C.C. Kartha, RGCB, Trivandrum)

22.06.2017 to 21.06.2021

 

DBT

 

Rs. 87,52,800 /- (my share – Rs. 25,60,400) + Rs.60 lacs as special grant

Development of Hemoglobin based artificial oxygen carrier: Engineering recombinant and packaged hemoglobin (as PI; Co-PI – Prof. Alo Nag)

13.06.2018 to

12.06.2021.

DRDO (Life Sciences Research Board)

Rs.65,43,392

 

Minor Project

 

Understanding the structure of Leishmania major phosphopantetheinyl transferase (LmjPPTase) and its interaction with cognate ACP (Phase II)

27.3.2015 to 31.3.2019

 

UGC-DAE Consortium of Scientific Research

Rs.13,17,000

Understanding the structure of Leishmaniaamajor Phosphopantetheinyl Transferase (Lmj PPTase) and its interaction with cognate ACP

1st April 2018 to 31st March 2019

UGC-DAE Consortium for Scientific Research

 Rs.2,63,400

Patents


  • “Engineering Enhanced Heme Retention in Hemoglobin”, Amit Tyagi, Suman Kundu, Mohd. Asim Khan, Kajal Yadav, Nidhi Mittal, Gaurav Mittal, Indian Ordinary Patent Application No 202211073665, December 19, 2022. (Applicants: Chairman, Defence Research & Development Organisation & University of Delhi; Our Ref:  ERIP/IP/2101007/M/01; DRDO Ref: SKL:SKT: P_IN101243).
  • “Isolated Polynucleotide Molecules Corresponding to Mutant and Wild-type Alleles of the Maize D9 Gene and Methods of Use”. (2007). Lawit, Shai J.;  Kundu, Suman; Rao, Aragula, G.; Tomes, Dwight T. US Patent 7,557,266; EP Patent 2,251,349; WO Patent 2,007,124, 312. Pioneer Hi-Bred International, Inc., Johnston, Iowa, USA

Editing / Reviewing


  • Guest Editor (2022): “Symmetry in Protein Architecture: Evolution, Design, Structure-function Relationship and Applications", Topic Editors: Suman Kundu and Michael Blaber; Topic Coordinator: Sanjay Kumar Dey, Frontiers in Molecular Biosciences.
  • External reviewer for Qatar University (QU), Internal Grants – iGrants 2022
  • Founder Editor-in-Chief of Journal of Proteins and Proteomics (Springer Nature)
  • Peer Reviewed articles for FEBS Letters, Journal of Agriculture and Food Chemistry, Indian Journal of Microbiology, Indian Journal of Biotechnology, Cell and Development Biology, PLoS One, Scientific Reports (Nature Publishing Group), Protein Science, International Journal of Biological Macromolecules, Drug Design, Development and Therapy, Indian Journal of Medical Research, Proteins: Structure, Function, Bioinformatics, Journal of Biomolecular Structure and Dynamics, BMC Molecular and Cell Biology, Therapeutics and Clinical Risk Management, Oncology Letters, Applied Biochemistry and Biotechnology, Letters in Drug Design and Discovery, F1000 Research, Journal of Proteomics.
  • Reviewed grant proposals for DBT, DST, CSIR, IIT Delhi.
  • Reviewed Ph.D / M/Phil Theses - ~40 (forty)

MoU / CRA


Memorandum of Agreement to “Develop a Machine Learning (ML) / Artificial Intelligence (AI) model to detect beta thalassemia trait using CBC parameters” with ICMR-National Institute of Immunohematology (NIIH), KEM Hospital Campus, Parel, Mumbai for 1 year from 8th March, 2023. Scientists from NIIH – Dr. Manisha Madkaikar and Dr. Naveen Khargekar; Scientists from BITS Goa – Dr. Snehanshu Saha.

 

Collaborative Research Agreement on "Pathophysiological investigations of Sickle Cell Disease and Interventions to improve associated Hemorheological Abnormalities" with Sri Sri College of Ayurvedic Science and Research Hospital, Sri Sri University, Cuttack, Odisha for 5 years from December 9, 2021.

 

Collaborative Research Agreement (CRA or MoU) with M/s Sai Phytoceuticals Pvt. Ltd, New Delhi, India for the project entitled “Pathophysiological investigations of sickle cell disease and interventions to improve associated hemorheological abnormalities”, for 5 years from 20th October, 2021

 

Collaborative Research Agreement (CRA or MoU) effective from 11th December, 2020 with M/s Sai Phytoceuticals Pvt. Ltd., Greater Kailash Part II, New Delhi 110048 (Mr Anil Bhansali) on the topic “New Drug Candidates to Combat Hypertension and Cardiac Hypertrophy Designed against an Unconventional Target and Pathway”

 

Collaborative Research Agreement (CRA or MoU) effective from 7th November, 2017 for 5 years with All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029 (Prof. S.K Maulik, Department of Pharmacology) on the topic “Scientific validation of medicinal plant extracts and their constituents in regulating pulmonary and systemic hypertension vis-à-vis catecholamine biosynthetic, NO metabolism and redox pathways

 

Collaborative Research Agreement (CRA or MoU) effective from 7th November, 2017 for 5 years with All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029 (Prof. S.K Maulik, Department of Pharmacology) on the topic Development and screening of potent small molecule inhibitors against dopamine beta-hydroxylase and nicotinamide adenine dinucleotide phosphate oxidase to combat pulmonary hypertension

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