BITS Pilani

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Research

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Research

Area of interest

  • Computer Aided Drug Design including Chemoinformatics.
  • Synthetic Medicinal Chemistry of Non-Nucleosidal Reverse Transcriptase Inhibitors and its' allied opportunistic infections such as TB, Malaria and Leishmaniasis.
  • Synthetic Medicinal Chemistry of rare disorders such as Sickle Cell Disease, Gaucher's disease, etc
  • New analytical method development and validation of API, Dosage forms by using various instrumental analytical techniques.

Research Grants and Funds Completed

Research Initiation Grant from Birla Institute of Technology and Science, Pilani entitled "Design, Synthesis and Study of novel Benzopiperidine analogs as HIV-1 Reverse Transcriptase Inhibitors". Duration 2 Years (Dec.2011 to Dec. 2013) 

DST Science & Engineering Research Board, Fast Track Young Scientist, New Delhi entitled "Design, Synthesis and Evaluation of novel Tetrahydroquinoline and Tetrahydroisoquinoline analogs as anti-HIV agents". Duration 3 Years (May, 2012 to May, 2015) 

Research Proposal entitled “Synthesis and Bioactivity of Novel Benzodiazepine Derivatives” (Ref. No: PY/2017/01535), Research University Grant Scheme-UTM, Malaysia. Duration: 1 Year, Amount (50000 RM / 8.00 Lakh) (Feb. 2018 to Jan. 2019), Dated: 24-10-2017) 

Research Proposal entitled "Development of novel anti-leishmanial analogues loaded with novel nano-formulations" DBT, Indo-Spanish Joint Programme for Technological Co-operation in Biotechnology under the scheme of ISIP. Duration: 3 Years, Amount: 60 Lakhs (March, 2018 to September 2021) Dated: 26-3-18. Ref: BT/IN/Spain/39/SM/2017-18 to 25-3-2021. 

Research Proposal entitled “Optimization, design and synthesis of novel lead molecules against multiple targets of SARS CoV-2” AICTE, DDH-2020 Phase-II. Duration: 1 Year, Amount (14.35 Lakh) (June, 2021 to May, 2022) Dated: 09-06-2021. 

Research Proposal entitled “The ‘sySTEMs’ initiative: systems biology-augmented, stem cell-derived, multi-tissue panel for rapid screening of approved drugs as potential COVID-19” (Ref. No: MRF2009092) NHMRC, MRFF, Australia. Duration: 1 Year, Amount (25.77 Lakh) (August, 2021 to January, 2024) Dated: 02-08-2021

Research Grants and Funds Sanctioned

Research Proposal entitled “Interdisciplinary Life Science Programme for Advanced Research and Education in Epigenetics and Genome editing” (Ref. No:102/IFD/SAN/1226/2021-2022; Dated: 24-09-2021) DBT-BUILDER, New Delhi - University of Birla Institute of Technology and Science Pilani, Pilani Campus. Other PI / Co-PI, Dr. A K Das, Dr. Atish Paul, Dr. Deepak Chitkara, Dr. Prabhat N Jha, Dr. Syamantak Majumder, Prof. Hemant R Jadhav, Prof. Rajdeep Chowdhury, Dr. Anupama Mittal, Prof. Rajeev Taliyan, Dr. Gaikwad Anil, Dr. Sandeep Sundriyal. Duration: 5 Years, Amount (90180320 Lakh) (24th September 2021 to 23rd September 2026) Dated: 24-09-2021 

Research Proposal entitled “Lipogenic Stearoyl CoA Desaturase (SCD) as a Promising Anti-Obesity and Anti-NAFLD Target: High-Throughput Screening and Biochemical Validation of Synthetic and Natural Product Molecules(Ref. No: 2021-12969) ICMR, New Delhi, India. Duration: 2 Years, Amount (15.96 Lakh) (April, 2022 to March, 2024) Dated: 21-04-2022 

Research Proposal entitled “Synthesis, Anti-HIV Evaluation and in silico Study of Novel Coumarin-chalcone Hybrids” (Ref. No: FRGS/1/2022/STG04/UTM/02/4), Fundamental Research Grant Scheme (FRGS) Malaysia. Duration: 3 Years, Amount (RM 191,000; 34.03 Lakh) (September 2022 to August 2025), Dated: 17-08-2022 

Research Proposal entitled “Design, synthesis and evaluation of novel Thiochromene analogs as potential anti-leishmanial agents” (Ref. No: CRG/2022/005290), DST-SERB CRG, NewDelhi. Duration: 3 Years, Amount (42.03 Lakh) (February, 2023 to January, 2026), Date: 21-02-2023 

Research Proposal entitled “Discovery and Biological Evaluation of Novel Dual Inhibitors of DprE1 and InhA as Potential Anti-Tubercular Agents” (Ref. No: CRG/2022/001889), DST-SERB CRG, NewDelhi. Duration: 3 Years, Amount (48.93 Lakh) (February, 2023 to January, 2026), Date: 21-02-2023

Research Grants and Funds Applied

Design, Synthesis and Anti-HIV Bioassay of Novel Hybrids Natural Products with Thiazolidinone Derivatives, Dr. Joazaizulfazli Jamalis (PI), Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310, Skudai, Johor, Malaysia., UTM Fundamental Research Grants - 2022, Duration in Months: -24, Rs. 2,105,000 INR 

Modulating Energy-Nutrient Sensor, AMP-activated Kinase (AMPK), for Treatment of Metabolic Syndrome: High-Throughput Virtual Screening of Small Molecule Activators and Global Phosphoproteomic Elucidation of Cell Signalling Mechanisms, Dr. P. R. Deepa (PI) and Dr. Pankaj Kumar Sharma (Co-PI), Department of Biological Sciences, BITS Pilani, Pilani Campus, Pilani, DST New Delhi, Duration in Months: 36, Rs. 2,390,000 INR 

Targeting Lipid-Sensing Nuclear Receptors (PPARs) in Controlling Non-Alcoholic Fatty Liver Disease (NAFLD)/Non-Alcoholic Steatohepatitis (NASH) Progression: Biochemical Investigation of Pan-PPAR (α/γ/β/δ) Agonists as Potential Pharmacological Agents, Dr.P. R. Deepa (PI) and Dr. Pankaj Kumar Sharma (Co-PI), Department of Biological Sciences, BITS Pilani, Pilani Campus, Pilani, ICMR New Delhi, Duration in Months: 36, Rs. 35,60,000 INR 

Treatment of Infectious Disease in the GI Tract against H. Pylori using Macrophage-targeted Fucoidan-Boswallic Acid Nano particles. Dr. S. Sathianarayanan (PI), DBT New Delhi, Duration in Months: 36, 43,41,000 INR

Thesis Guidance

B. Pharm 50 (Completed) and 01 (On Going)
M. Pharm 31 (Completed) and 01 (On Going)
Ph. D 05 (Completed), 05 (On Going as Supervisor) and 03 (On Going as Co-supervisor)

An Institution Deemed to be University estd. vide Sec.3 of the UGC Act,1956 under notification # F.12-23/63.U-2 of Jun 18,1964

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