Cloning and Expression of Gyrase A of Plasmodium falciparum.
Mentor: Dr. Saman Habib, Scientist C, CDRI, Lucknow
Malarial Parasite (Plasmodium falciparum) was target using apicoplast genome as it does not has any reliable medicine to act on still. I targeted Gyrase because it is very important to maintain the linking number and coiling along with the proper negative supercoiling.
Contig Design and in-silico Gene Prediction
Mentor: Dr.CVS Sivaprasad , Scientist C , BioInformatics
I found out contigs on system for selected genes and designed contigs using Blast searches and did the Modeling Simulation for it too.
Heavy Metal Removal from Industrial Waste
Mentor: Dr. SK Verma, Associate Professor, BITS, Pilani
An extensive study was carried out on the concepts involved and the industrial applications of the Purification Systems with specific importance given to the Cyanobacteria.
Homology Modeling of a Hypothetical Cell Surface Protein AMA1 of Plasmodium falciparum using Modeller 8
Mentor: Dr. Shibashish Chowdhary, Assistant Professor, BITS, Pilani
An arbitrary protein was taken and model is designed for that using BioInformatics tools to target Malarial Parasite
Micropropagation of medicinally important plant species like Citrus limon &Withania somnifera.
Mentor: Dr. Jitendra Panwar, Assistant Professor, BITS, Pilani
This was a lab oriented project in which I have standardized the initial parameters in the issue culture of this plant species like the standardization of the growth hormone concentration for the shoot initiation process.
ELISA analysis of various peptide variants of the epitope of AMA1 (Apical Membrane Antigen 1)
Mentor: Dr. Vidya Rajesh, Assistant Professor, BITS, Pilani
Here we screened the blood of various malaria patients to check the epitope variant present using ELISA.
Identification of Epitopes of Plasmodium Vivax Ama1 Using Bioinformatics Tools and Study of Immunological Properties of Expressed Protein.
Mentor: Dr. Vidya Rajesh, Assistant Professor, BITS, Pilani
Here we traced the probable epitopes in AMA1 gene for giving insight about the role of this antigen in the malaria.